Topical Skin Care

Topical skin care is an industry. We need to get practical when choosing topicals.  Many cosmeticeuticals seem to have a true pharmacologic effects (drug effects) although it is not legal to make such claims in the U.S. unless the product is already classified as a drug.  The process to  approve a topical as a drug is an expensive one. Therefore cosmeceuticals have not been scrutinized as have the retinoid family of topical drugs.
For topical skin care to have an impact, application has to be consistent.  Topicals cannot resurface the skin nor remove deep lines, unlike medical procedures. Yes, you make observe some immediate improvement  but this is usually a temporary effect of hydration or temporary tightening due to peptides contained in  some cosmetics.  We can't argue with an immediate favorable effect.  However,  we should seek to preserve our appearance, minimize signs of photoaging such as brown spots, fine lines and skin laxity and slow the aging process.  The younger we start with daily topical care, the better the end game will be. Over a period of years to decades, proper skin care can prevent the development of a significant amount of skin aging, not to mention reduce skin cancer risk. 

When a skin disease is present,  such as acne or rosacea, there are many excellent prescription topicals that can help more than most cosmeceuticals.
If you suffer with melasma,  breakouts, rosacea or acne then your dermatologist will likely prescribe a combination of topical(s) and/or oral medications.  If you are here for antiaging advice, the recommendations are simpler:

1.  Sunscreen!!!   I prefer you choose only sunscreens that have a non-chemical active ingredient.  The active will be zinc oxide, titaneum dioxide and sometimes added iron oxide.  The downside to non-chemical sunscreens  is that they can be less cosmetically elegant than their chemical containing counterparts .  I recommend you shop where you can test the product such as at Sephora or Ulta. Try the many available brands such as Bare Minerals or Color Science.  If you need a quick fix, consider EltaMD chemical free tinted sunscreen. If possible,  choose a tinted mineral sunscreen in order to filter more visible and infrared light.  The higher end products have a palate of colors to better match your skin tone. Tinted minerals filter more of the various electromagnetic radiation that we now know as harmful. h  The product SPF should be at least a SPF30.  Minerals, unlike chemicals, do not degrade when exposed to sunlight, they are like "shiny flakes" that reflect the sunlight.  If you don't sweat or rub them off, one application may suffice for the day, but it's generally a good idea to reapply once during the day.   I recommend a layered approach to sunscreen application, apply  a cream based mineral first such as Bare Minerals "prime time" and then cover with a Mineral Powder.  Layering with mineral sunscreens improves UV protection.  Some mineral powders are available in tubes with brush attached making them easier to reapply.   

2.  Retinoid.  Retinoids differ from retinols!  Retinols are less effective cousins to retinoids.  Retinoids can be drying and make you a tad bit sun sensitive.  Retinoids are decades old and have yet to be deposed by ANY other substance for topical skin rejuvenation.  All retinoids are prescription items, except one;  Differin 0.1%.   Differin is  inexpensive and FDA approved as an over the counter anti-acne drug in the form of a  gel.  Purchase Differin 0.1%  at Target, Rite Aid, Longs Drug, or Amazon.  Like all retinoids, apply a pea sized amount over your face at night.  Avoid your lips and eye area.  If you are a bit dry, use it only 2-3 times a week until you can tolerate it more often.  Look for subtle but real results in 6 months (acne improvment in 6-12 weeks).  Never stop!  I see a lot of patients in their 70s +. Those who have used retinoids faithfully for a decade or more look amazing despite never having any laser or other cosmetic treatments.  Most all also used sunscreen faithfully and stayed out of the sun! If you want or can tolerate stronger retinoids you will need a prescription.  Ortho has a new Tretinoin (Altreno) 0.05% lotion in a moisturizing base (it is stronger than Differin 0.1%).  It is available for a flat fee of $115 at the pharmacy.  Altreno, like all tretinoin retinoids requires a doctor's prescription.  One tube will last about 3 months. Other prescription retinoids include   Adalapene (Differin) 0.3%  and Tazarotene (Tazorac).

3.  An antioxidant   This is the optional part of the equation.  If used in the morning,  antioxidants probably do buffer the sun's ability to damage skin DNA. You can change you antioxidant at will, feel free as it is not certain which, if any, are effective.   Go ahead and buy that $500 cream you've been wanting.  Or purchase one of the inexpensive Deciem (The Ordinary) antioxidants.  Skin Ceuticals is also a higher end and trusted name for topicals.  Which do I like?  I change my mind too so no guilt.  If you have excess pigmentation I like Skin Ceuticals Discoloration Defense or AzaClear Brightening pads (azelaic acid + niacinamide) typically sold back bar by the physician. For no particular reason,  I like Deciem's Resveratrol 3%/Ferulic Acid 3% (less than $10) has a nice formulation although for sensitive skin it might sting a bit.  Topical Vitamin C is a popular topical antioxidant (e.g. Skin Ceuticals 10% vitamin C), or use The Ordinary's version  30% Vitamin C suspension in silicone.  For rosacea,  AzaClear cream (azelaic acid + niacinamide) is one of my favorites.

Consistency is most important.  Keep it simple.  If you use the products (sunscreen and retinoid) and don't see a change, you are wrong!  There is slow but sure microscopic change, proven over many many decades by validated scientific reseach.  The changes in your skin include reversing microscopic sun damage. Have faith!


The only oral supplement that I recommend is Niacinamide.  Niacinamide has been shown to reduce skin pre-cancers in high risk individuals.  Whether it's antioxidant properties will help those of us who are not immune-suppressed or who have never developed skin cancer has not been investigated,  but it remains plausible.   Niacinamide orally may also help control acne and rosacea pustules.  The double blind, placebo controled study of niacinamide and skin cancer prevention in high risk individuals was published in the New England Journal of Medicine, a revered medical journal.  The dose found effective was 500mg  twice a day.  I recommend patients take 1000 mg as a single dose for simplicity once daily although 500mg twice a day may give more even blood levels.  Niacinamide 1000mg is easily found on Amazon and in most pharmacies.  

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